veterinary drug residues
The working group was founded in 1985 and consists of active and corresponding members from authorities and institutions involved in official food monitoring, independent private laboratories, the food industry and universities.
The active members meet twice a year in person or virtually for the working group meeting. Active and corresponding members have the option of viewing and downloading the minutes of the working group meetings on the internal working group pages (under www.gdch.de --> log in to MyGDCh with your membership number and password).
The main tasks of the working group include:
The results of its work are primarily incorporated into official testing activities, food production’s own control systems and the work of laboratories providing expert opinions.
Dr. Christian Hinkel
Bavarian State Office for Health
and Food Safety (LGL)
Tel.: 09131 68082191
Email: christian.hinkel@lgl.bayern.de
Dr. Dierk Clos
Tel.: 0261 9149-362
Email: dierk.clos@lua.rlp.de
Term of office: 2024 - 2026
The working group has set itself the objective of monitoring new developments in rapid test systems, alongside reviewing physico-chemical measurement methods such as LC-MS.
Following an extensive comparison of commercially available ELISA test kits, Premitest, as a rapid antibiotic test in organ material, was evaluated in several laboratories in comparison with the results of the three-plate inhibition test and chemical analytical methods.
The objective of validating analytical methods is to ensure the scientifically sound and legally compliant comparability of analytical results. Validation is part of quality assurance systems in accordance with DIN EN ISO / IEC 17025.
The analytical results from different laboratories within the EU and beyond must be comparable in terms of accuracy, trueness and precision. For analytical methods validated before 10 June 2021 as part of official residue controls, Decision 2002/657/EC will continue to apply in part until 10 June 2026 (Reference 1). For new validations or revalidations, the requirements of Implementing Regulation (EU) 2021/808 must be observed from 10 June 2021 onwards (Reference 4).
A subgroup of the working group prepared a proposed procedure for the practical implementation of validation in routine laboratories in accordance with the aforementioned EU Decision. Following discussion within the working group, this was published (Reference 2). In addition, various validation procedures were compared.
The results of these discussions were incorporated into the validation procedure recommended by the BVL using the “InterVal” software developed by quo data GmbH.
Links
BVL / BFR / EU
https://www.bfr.bund.de/de/lebensmittel-391.html
https://food.ec.europa.eu/safety/chemical-safety/residues-veterinary-medicinal-products_en
Literature
1) Commission Decision of 12 August 2002 implementing Council Directive 96/23/EC concerning the performance of analytical methods and the interpretation of results
(2002/657/EC)
2) Validation of methods for the analysis of pharmacologically active substances in the routine laboratory
food chemistry 57, 99 -102 (2003)
3) Discussion on the validation of methods for the analysis of pharmacologically active substances
food chemistry 58, 56-57 (2004)
4) COMMISSION IMPLEMENTING REGULATION (EU) 2021/808 of 22 March 2021 on the performance criteria for analytical methods used for residues of pharmacologically active substances in food-producing animals and on the interpretation of results, as well as on the methods to be used for sampling, and repealing Decisions
2002/657/EC and 98/179/EC
5) Targeted screening of veterinary medicinal products, food chemistry 75, 56 – 57 (2021)