This concept summarizes recent advancements in water-resistant organic room-temperature phosphorescence materials, emphasizing design strategies including supramolecular assembly, nanoparticle encapsulation, chromophore immobilization, and chromophore isolation. Additionally, it highlights the promising applications of these materials in bioimaging and information encryption. A forward-looking perspective is also provided on future developments in this field.

Organic room-temperature phosphorescence (RTP) materials have vitalized exponential attention in the fields of optoelectronics, information encryption, and biological imaging due to their unique luminescent properties. Nevertheless, achieving water-resistant RTP materials remains a major challenge, primarily due to the high sensitivity of triplet excitons to water-induced quenching. In this concept, the recent advances in the development of water-resistant RTP materials, including the design principles, detailed phosphorescence properties, and their potential applications, are summarized. In addition, it presents the current challenges and future perspectives on developing organic water-resistant RTP materials. This concept is expected to offer valuable insights for the design of high-performance organic water-resistant RTP materials and pave the way toward diverse practical applications in aqueous environments.