An electrochemical organic method for the direct synthesis of bis(indolyl)methane (BIM) derivatives is presented, with the reaction of hydrazones and indoles. This electrochemical approach, characterized by simple and mild reaction conditions, provides an operationally straightforward and practically applicable route to valuable indole derivatives, utilizing readily available raw materials.

An electrochemical organic method for the direct synthesis of bis(indolyl)methane (BIM) derivatives is presented, with the reaction of hydrazones and indoles. This developed approach is effective for aliphatic, aromatic, and heteroaromatic aldehydes, which react with a range of electron-rich and electron-poor indoles to produce the desired BIMs in good to excellent yields. Additionally, a potential antiobesity drug is also successfully synthesized with various indole derivatives under the influence of an electric current, and the transformation of BIMs demonstrates the application potential of this protocol.