The present personalized account summarizes various cyclization reactions, including multicomponent and domino processes, which are directed towards the synthesis of complex heterocyclic products. Reactions include, for example, various domino Knoevenagel /cyclization reactions, formal [3+3] cyclizations of pyridinium salts and of thioxindoles with fluoroaroyl chlorides, cyclizations of heterocyclic enamines with diimines and triazines, formal [3+3] cyclizations of 2,4,6-tris(trifluoromethyl)-1,3,5-triazine with 1,3-bis(silyloxy)-1,3-butadienes and domino [4+2] / retro [4+2] reactions of 2-ethynylpyridines with electron-rich dienes.